Epixel Watch: Market Trends and Insights
The global weight management industry is growing very fast these days, same is true for the US. Technological advancements in the weight management industry like fitness devices, mobile health apps and other coaching technologies are contributing to the market’s growth.
Today, North America is the largest market for weight management and US holds the largest market share. This is due to many reasons like having a well-established healthcare infrastructure, disposable income and popularity of wellness brands. There is a huge scope for new weight management companies in the country, as there is a need for fitness centres to address obesity and health issues.
List of the top MLM weight management companies in the USA
The MLM companies in the US are very popular among its citizens; many have included direct selling in their daily lives as a means of part-time or full-time income. Weight management is a growing sector in the US MLM industry. Below is a list of the top weight management companies in the country:
Data updated in July 2025
*The above list is subject to market changes and modifications.
Explore the top 100 MLM companies in the world which are inventing new trends and contributing to the network marketing economy.
Insight into the top MLM weight management companies in the US
Herbalife
Herbalife
Herbalife is a leading network marketing weight management company in the US. It was established in 1980 and offers different kinds of nutritional products for health and weight loss. It offers products like meal replacement shakes and provides various training and classes by professionals for losing weight and maintaining a healthy lifestyle. Herbalife’s weight loss products are varieties of Formula 1 Nutritional Shake, Cell-U-Loss and Herbal Control.
Country: USA
Website: www.herbalife.com
Top Earners: 10
Products & Services: Personal Care & Wellness,Food & Beverage, Cosmetics
Founder: Mark R. Hughes
CEO: Michael O. Johnson
Year Founded: 2010
Headquarters: Los Angeles, California, USA
Achievements:
- Ranked #2 on the DSN Global 100 list for 2025.
- Achieved a Guinness World Records™ title for the 2024 Global Workout Event.
- Honored with the Direct Selling Association's Excellence in Business Award.
Nu Skin Enterprises
Nu Skin Enterprises
Nu Skin is a wellness MLM company that offers a weight management program called ageLOC TR90. The program offers personalized services for weight management; in it, they provide healthy and innovative products like supplements and shakes, a balanced diet plan and encourage an active lifestyle.
Country: USA
Website: www.nuskin.com
Top Earners: 68
Products & Services: Personal care and dietary supplements
Founder: Blake Roney, Steven Lund, Sandra Tillotson
CEO: Ryan Napierski
Year Founded: 1984
Headquarters: Provo, Utah, United States
Achievements:
- Ranked #11 in 2025 DSN Global 100.
- Received the Direct Selling Association (DSA) Award for Product Innovation.
- Honored with the 2024 BIG Innovation Award for Nu Skin's ageLOC® WellSpa iO®.
Forever Living Products
Forever Living Products
Established in 1978, Forever Living Products is a wellness MLM company founded by Rex Maughan. It’s a multi-billion-dollar company that offers many products in the beauty, wellness, and weight management categories. In the weight management segment, they offer products for weight loss or muscle building; they provide products like tablets, bars, capsules, soft gels and shakes.
Country: USA
Website: www.foreverliving.com
Top Earners: 16
Products & Services: Cosmetics, personal care
Founder: Rex Maughan
CEO: Gregg Maughan
Year Founded: 1978
Headquarters: Scottsdale, Arizona, United States
Achievements:
- Secured the 2023 Global Green Beauty Awards.
- Earned the 2023 Nourish Awards.
- Recognized as the winner of the SITE Crystal Award in 2022.
USANA
USANA
USANA Health Sciences, Inc. is one of the top MLM weight management companies in the US. USANA provides many products and programs for weight loss. It has developed the Active Nutrition Jumpstart Program to help people lose weight by providing specially crafted food products. For example, for a day they provide meal-replacement shakes, fruits, vegetables, a probiotic supplement, a metabolism supplement, and two vitamin packs.
Country: USA
Website: https://www.usana.com/
Top Earners: 35
Products & Services: Haircare/Hair Accessories, Health/Fitness/Wellness, Nutritional Supplements, Oral Hygiene, Personal Care, Skincare, Weight Management
Founder: Myron Wentz, Ph.
CEO: Jim Brown
Year Founded: 1992
Headquarters: Salt Lake City, Utah, USA
Achievements:
- Ranked #15 on the DSN Global 100 list for 2025.
- Won five awards in the Best of State Awards.
- Won the Malaysia Management Excellence Awards 2024.
Medifast
Medifast
Optavia is a brand under Medifast that offers various products and services related to health, wellness, fitness and weight management. They provide various training programs led by trained professionals to help you achieve your fitness goals. Various types of weight loss and health products are also offered by the company.
Country: USA
Website: www.optavia.com
Top Earners: 2
Products & Services: Health/Fitness/Wellness, Weight Management
Founder: Wayne Scott Andersen
CEO: Daniel R. Chard
Year Founded: 2002
Headquarters: Baltimore, Maryland, United States
Achievements:
- Ranked #19 in 2025 DSN Global 100.
- Named to US News & World Report’s List of Best Companies to Work For within the food and drink industry.
Shaklee
Shaklee
Shaklee is a famous network marketing company that has been operating since 1956. Their scientists have designed a simple program for reducing weight and maintaining a healthy weight balance. In the program, they offer weight loss products like Five Day Reset, Reset & Thrive, 7-Day Health Cleanse, Metabolic Boost and Life Shake.
Country: USA
Website: https://us.shaklee.com/en_US/s/
Top Earners: 2
Products & Services: Wellness
Founder: Forrest Shaklee
CEO: Roger Barnett
Year Founded: 1956
Headquarters: Pleasanton, California, USA
Achievements:
- Won Trusted Brand Award 2022.
- Reader's Digest Trusted Brand GOLD Award in the Vitamins and Health Supplements category.
Isagenix International
Isagenix International
Isagenix is an international company that mainly focuses on health and wellness. They offer a range of products for weight loss, and it includes many systems, bars, shakes and snacks. Its weight loss system contains different packs such as 30-Day Reset, 9-Day Deep Cleansing System, Bedtime Belly Buster, Weight Loss Premium Pack, etc.
Country: USA
Website: www.isagenix.com
Top Earners: 16
Products & Services: Essential Oils, Health/Fitness/Wellness, Nutritional Supplements, Personal Care, Skincare, Weight Management
Founder: John Anderson, Jim Cover, and Kathy Cover
CEO: Sharron Walsh
Year Founded: 2002
Headquarters: Gilbert, Arizona, United States
Achievements:
- Recognized as a Top Company to Work for in Arizona (2021)
- Won the 2020 AZ Business Angels Award for Outstanding Corporate Responsibility.
- Ranked in the Direct Selling Association's Top 20 based on U.S. net sales.
Plexus Worldwide Inc.
Plexus Worldwide Inc.
Plexus Worldwide is an MLM company that focuses on the gut health space. It mainly produces gut health and microbiome products. Plexus has been operating since 2008 and has many patented products designed by its scientists. The company also provides a weight management system to ensure the overall wellness of its customers. Its product line for weight loss includes Plexus Reset, Weight Loss Continuation Combo, Lean Vegan Twin Pack, etc.
Country: USA
Website: www.plexusworldwide.com
Top Earners: N/A
Products & Services: Weight Management
Founder: Tarl Robinson, Alec Clark
CEO: Gene Tipps
Year Founded: 2008
Headquarters: Scottsdale, Arizona, United States
Achievements:
- Ranked #30 in 2024 DSN Global 100.
- DSA honors for Excellence in Marketing and Sales for Plexus Reset.
- Recognized as Industry Leader in Creativity and Innovation.
LifeVantage
LifeVantage
LifeVantage is a wellness company that offers products for weight loss, aging and overall wellbeing. Its weight management products are MindBody GLP-1 System and PhysIQ Fat Burn. The company also claims to give importance to quality and eco-friendly products that are free from harmful chemicals.
Country: USA
Website: www.lifevantage.com
Top Earners: 16
Products & Services: Animal/Pet Care, Health/Fitness/Wellness, Nutritional Supplements, Skincare, Weight Management
Founder: Darren Jensen
CEO: Steven Fife
Year Founded: 2003
Headquarters: Lehi, Utah,USA
Achievements:
- LifeVantage Honored As Gold & Bronze Stevie Award Winner In 2020 American Business Awards.
- LifeVantage Honored as Stevie® Award Winner in 2019 American Business Awards.
Mannatech, Inc.
Mannatech, Inc.
Mannatech, Inc. is an international multi-level marketing company that provides dietary supplements, weight management products and personal care products. The company was founded in 1993 by Samuel Caster and has its headquarters in Flower Mound, Texas. They provide various products for fitness and weight management. Its product line includes OsoLean, Tru Fat Burner, SPORT, TruHealth 30-Day System, etc.
Country: USA
Website: https://www.mannatech.com
Top Earners: 1
Products & Services: Dietary supplements and personal care products
Founder: Samuel Caster
CEO: Landen Fredrick
Year Founded: 1993
Headquarters: Dallas, Texas, United States
Achievements: N/A
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Many multi-level marketing companies' efforts to provide natural and toxin-free products have attracted a lot of health-conscious consumers towards them. Due to this growing trend of health and fitness, there is immense scope for weight management and fitness companies in the US.
Disclaimer: Epixel neither promotes nor supports any of the companies mentioned in this article nor their products or services. The facts published here are represented as reported in the direct selling industry. The facts don't reflect our priorities. The article was compiled based on available resources and does not represent special mentions or priorities to organizations, persons, or products.
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